WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_AACTTT_UNKNOWN       ID:DB_ID:1851
C=1859; O=13; E=2.67; R=4.86; rawP=1.96e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000047457 NA CP ceruloplasmin (ferroxidase) 1356 ENSG00000047457
2  ENSG00000149131 NA SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 710 ENSG00000149131
3  ENSG00000167601 NA AXL AXL receptor tyrosine kinase 558 ENSG00000167601
4  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
5  ENSG00000244414 NA CFHR1 complement factor H-related 1 3078 ENSG00000244414
6  ENSG00000153823 NA PID1 phosphotyrosine interaction domain containing 1 55022 ENSG00000153823
7  ENSG00000130558 NA OLFM1 olfactomedin 1 10439 ENSG00000130558
8  ENSG00000134363 NA FST follistatin 10468 ENSG00000134363
9  ENSG00000172935 NA MRGPRF MAS-related GPR, member F 116535 ENSG00000172935
10  ENSG00000119655 NA NPC2 Niemann-Pick disease, type C2 10577 ENSG00000119655
11  ENSG00000100889 NA PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 5106 ENSG00000100889
12  ENSG00000139910 NA NOVA1 neuro-oncological ventral antigen 1 4857 ENSG00000139910
13  ENSG00000173040 NA EVC2 Ellis van Creveld syndrome 2 132884 ENSG00000173040


Database:Transcription Target       Name:hsa_TGGAAA_V$NFAT_Q4_01       ID:DB_ID:2437
C=1871; O=12; E=2.69; R=4.46; rawP=1.23e-05; adjP=0.0010
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198483 NA ANKRD35 ankyrin repeat domain 35 148741 ENSG00000198483
2  ENSG00000112290 NA WASF1 WAS protein family, member 1 8936 ENSG00000112290
3  ENSG00000138172 NA CALHM2 calcium homeostasis modulator 2 51063 ENSG00000138172
4  ENSG00000139178 NA C1RL complement component 1, r subcomponent-like 51279 ENSG00000139178
5  ENSG00000153823 NA PID1 phosphotyrosine interaction domain containing 1 55022 ENSG00000153823
6  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
7  ENSG00000122121 NA XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 7512 ENSG00000122121
8  ENSG00000134363 NA FST follistatin 10468 ENSG00000134363
9  ENSG00000172935 NA MRGPRF MAS-related GPR, member F 116535 ENSG00000172935
10  ENSG00000149115 NA TNKS1BP1 tankyrase 1 binding protein 1, 182kDa 85456 ENSG00000149115
11  ENSG00000134853 NA PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5156 ENSG00000134853
12  ENSG00000188783 NA PRELP proline/arginine-rich end leucine-rich repeat protein 5549 ENSG00000188783


Database:Transcription Target       Name:hsa_CAGGTG_V$E12_Q6       ID:DB_ID:2409
C=2450; O=13; E=3.52; R=3.69; rawP=3.76e-05; adjP=0.0012
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
2  ENSG00000169155 NA ZBTB43 zinc finger and BTB domain containing 43 23099 ENSG00000169155
3  ENSG00000131446 NA MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 4245 ENSG00000131446
4  ENSG00000167601 NA AXL AXL receptor tyrosine kinase 558 ENSG00000167601
5  ENSG00000167995 NA BEST1 bestrophin 1 7439 ENSG00000167995
6  ENSG00000151491 NA EPS8 epidermal growth factor receptor pathway substrate 8 2059 ENSG00000151491
7  ENSG00000137809 NA ITGA11 integrin, alpha 11 22801 ENSG00000137809
8  ENSG00000134363 NA FST follistatin 10468 ENSG00000134363
9  ENSG00000172935 NA MRGPRF MAS-related GPR, member F 116535 ENSG00000172935
10  ENSG00000197859 NA ADAMTSL2 ADAMTS-like 2 9719 ENSG00000197859
11  ENSG00000134853 NA PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5156 ENSG00000134853
12  ENSG00000170577 NA SIX2 SIX homeobox 2 10736 ENSG00000170577
13  ENSG00000188783 NA PRELP proline/arginine-rich end leucine-rich repeat protein 5549 ENSG00000188783


Database:Transcription Target       Name:hsa_V$IPF1_Q4       ID:DB_ID:2100
C=256; O=5; E=0.37; R=13.59; rawP=3.48e-05; adjP=0.0012
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000181804 NA SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 285195 ENSG00000181804
2  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
3  ENSG00000130558 NA OLFM1 olfactomedin 1 10439 ENSG00000130558
4  ENSG00000197859 NA ADAMTSL2 ADAMTS-like 2 9719 ENSG00000197859
5  ENSG00000187634 NA SAMD11 sterile alpha motif domain containing 11 148398 ENSG00000187634


Database:Transcription Target       Name:hsa_RTAAACA_V$FREAC2_01       ID:DB_ID:2417
C=907; O=8; E=1.30; R=6.14; rawP=4.60e-05; adjP=0.0012
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
2  ENSG00000188001 NA TPRG1 tumor protein p63 regulated 1 285386 ENSG00000188001
3  ENSG00000166888 NA STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 6778 ENSG00000166888
4  ENSG00000124212 NA PTGIS prostaglandin I2 (prostacyclin) synthase 5740 ENSG00000124212
5  ENSG00000167601 NA AXL AXL receptor tyrosine kinase 558 ENSG00000167601
6  ENSG00000187634 NA SAMD11 sterile alpha motif domain containing 11 148398 ENSG00000187634
7  ENSG00000172935 NA MRGPRF MAS-related GPR, member F 116535 ENSG00000172935
8  ENSG00000134363 NA FST follistatin 10468 ENSG00000134363


Database:Transcription Target       Name:hsa_TTGTTT_V$FOXO4_01       ID:DB_ID:2416
C=2037; O=12; E=2.93; R=4.10; rawP=2.86e-05; adjP=0.0012
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000115380 NA EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2202 ENSG00000115380
2  ENSG00000112290 NA WASF1 WAS protein family, member 1 8936 ENSG00000112290
3  ENSG00000197965 NA MPZL1 myelin protein zero-like 1 9019 ENSG00000197965
4  ENSG00000166888 NA STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 6778 ENSG00000166888
5  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
6  ENSG00000130558 NA OLFM1 olfactomedin 1 10439 ENSG00000130558
7  ENSG00000182326 NA C1S complement component 1, s subcomponent 716 ENSG00000182326
8  ENSG00000134363 NA FST follistatin 10468 ENSG00000134363
9  ENSG00000172935 NA MRGPRF MAS-related GPR, member F 116535 ENSG00000172935
10  ENSG00000139910 NA NOVA1 neuro-oncological ventral antigen 1 4857 ENSG00000139910
11  ENSG00000134853 NA PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5156 ENSG00000134853
12  ENSG00000233608 NA TWIST2 twist homolog 2 (Drosophila) 117581 ENSG00000233608


Database:Transcription Target       Name:hsa_V$MEIS1BHOXA9_01       ID:DB_ID:2087
C=144; O=4; E=0.21; R=19.32; rawP=5.72e-05; adjP=0.0013
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000178718 NA RPP25 ribonuclease P/MRP 25kDa subunit 54913 ENSG00000178718
2  ENSG00000130558 NA OLFM1 olfactomedin 1 10439 ENSG00000130558
3  ENSG00000139910 NA NOVA1 neuro-oncological ventral antigen 1 4857 ENSG00000139910
4  ENSG00000187634 NA SAMD11 sterile alpha motif domain containing 11 148398 ENSG00000187634


Database:Transcription Target       Name:hsa_AAAYRNCTG_UNKNOWN       ID:DB_ID:1846
C=368; O=5; E=0.53; R=9.45; rawP=0.0002; adjP=0.0035
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000134363 NA FST follistatin 10468 ENSG00000134363
2  ENSG00000094880 NA CDC23 cell division cycle 23 homolog (S. cerevisiae) 8697 ENSG00000094880
3  ENSG00000131446 NA MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 4245 ENSG00000131446
4  ENSG00000134853 NA PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5156 ENSG00000134853
5  ENSG00000188783 NA PRELP proline/arginine-rich end leucine-rich repeat protein 5549 ENSG00000188783


Database:Transcription Target       Name:hsa_TGACAGNY_V$MEIS1_01       ID:DB_ID:2432
C=819; O=7; E=1.18; R=5.95; rawP=0.0002; adjP=0.0035
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000181804 NA SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 285195 ENSG00000181804
2  ENSG00000198483 NA ANKRD35 ankyrin repeat domain 35 148741 ENSG00000198483
3  ENSG00000134853 NA PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5156 ENSG00000134853
4  ENSG00000149115 NA TNKS1BP1 tankyrase 1 binding protein 1, 182kDa 85456 ENSG00000149115
5  ENSG00000197859 NA ADAMTSL2 ADAMTS-like 2 9719 ENSG00000197859
6  ENSG00000147257 NA GPC3 glypican 3 2719 ENSG00000147257
7  ENSG00000187634 NA SAMD11 sterile alpha motif domain containing 11 148398 ENSG00000187634


Database:Transcription Target       Name:hsa_V$TGIF_01       ID:DB_ID:2084
C=243; O=4; E=0.35; R=11.45; rawP=0.0004; adjP=0.0041
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198483 NA ANKRD35 ankyrin repeat domain 35 148741 ENSG00000198483
2  ENSG00000169155 NA ZBTB43 zinc finger and BTB domain containing 43 23099 ENSG00000169155
3  ENSG00000134853 NA PDGFRA platelet-derived growth factor receptor, alpha polypeptide 5156 ENSG00000134853
4  ENSG00000149115 NA TNKS1BP1 tankyrase 1 binding protein 1, 182kDa 85456 ENSG00000149115




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).